Article

Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds

2025-01-14

Abstract excerpt

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory cytokine IL10 regulates these processes in the intestines of mice and humans; the anti-inflammatory activity of IL10 is also conserved in birds. To determine the function of IL10 in avian mucosal immunity, we generat...

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Literature Corpus work: 9c787c75-6dc9-59f6-ba1f-ce55b96f106b
DOI: 10.1101/2025.01.10.632125

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