Article

Endoglin deficiency elicits hypoxia-driven congestive heart failure in zebrafish

2021-10-09

Abstract excerpt

Hereditary hemorrhagic Telangiectasia (HHT) is a rare genetic disease relying on mutations affecting components of Bone Morphogenetic Protein and Transforming Growth Factor-β (BMP/TGF-β) signaling pathway in endothelial cells. This disorder is characterized by arterio-venous malformations prone to rupture. and ensuing hemorrhages are responsible for iron deficiency anemia. Along with Activin receptor-like kinase A...

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Literature Corpus work: 9c30f1fb-ec44-533c-bdbb-4563508e59d8
DOI: 10.1101/2021.10.09.463775

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