Article
Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children.
European child & adolescent psychiatry - 1 Oct 2016
Dadds Mark R, Schollar-Root Olivia, Lenroot Rhoshel, Moul Caroline, Hawes David J
Abstract excerpt
Recent evidence suggests that epigenetic regulation of the DRD4 gene may characterise specific aspects of ADHD symptomology. We tested associations between ADHD symptoms and epigenetic changes to the DRD4 gene in DNA extracted from blood and saliva in N = 330 children referred for a variety of behavioural and emotional problems. ADHD was indexed using DSM diagnoses as well as mother, father, and teacher reports....
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