Article
Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation.
Journal of neurodevelopmental disorders - 16 Aug 2020
Goodman Sarah J, Burton Christie L, Butcher Darci T, Siu Michelle T, Lemire Mathieu, Chater-Diehl Eric, Turinsky Andrei L, Brudno Michael, Soreni Noam, Rosenberg David, Fitzgerald Kate D, Hanna Gregory L, Anagnostou Evdokia, Arnold Paul D, Crosbie Jennifer, Schachar Russell, Weksberg Rosanna
Abstract excerpt
BACKGROUND: A growing body of research has demonstrated associations between specific neurodevelopmental disorders and variation in DNA methylation (DNAm), implicating this molecular mark as a possible contributor to the molecular etiology of these disorders and/or as a novel disease biomarker. Furthermore, genetic risk variants of neurodevelopmental disorders have been found to be enriched at loci associated...
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