Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The complexities underlying age-related macular degeneration: could amyloid beta play an important role?

1 Jan 2017

Abstract excerpt

Age-related macular degeneration (AMD) causes irreversible loss of central vision for which there is no effective treatment. Incipient pathology is thought to occur in the retina for many years before AMD manifests from midlife onwards to affect a large proportion of the elderly. Although genetic as well as non-genetic/environmental risks are recognized, its complex aetiology makes it difficult to identify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments
Share to Retinal Imaging and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28553324
DOI: 10.4103/1673-5374.205083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The complexities underlying age-related macular degeneration: could amyloid beta play an important role?PMID 28553324Read ↗

Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of MacrophagesSemantic proximity Read ↗

MicroRNA Expression Patterns Involved in Amyloid Beta–Induced Retinal DegenerationSemantic proximity Read ↗

Genetic and Epigenetic Biomarkers Linking Alzheimer's Disease and Age-Related Macular Degeneration.Semantic proximity Read ↗

Amyloid β accumulation and inner retinal degenerative changes in Alzheimer’s disease transgenic mouseSemantic proximity Read ↗

Mechanisms of age-related macular degeneration and therapeutic opportunities.Semantic proximity Read ↗

The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research.Semantic proximity Read ↗

Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function.Semantic proximity Read ↗

Age-related macular degeneration (AMD): pathogenesis and therapy.Semantic proximity Read ↗

Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration.Semantic proximity Read ↗

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.Semantic proximity Read ↗

Amyloid-β and Tau Pathology of Alzheimer's Disease Induced by Diabetes in a Rabbit Animal ModelSemantic proximity Read ↗

Genetic context modulates aging and degeneration in the murine retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.