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Exploration of Structural Optic Nerve Changes in Mouse Models of Retinal and Neuronal Degeneration with Optical Coherence Tomography

2026-04-14

Abstract excerpt

<h4>Purpose</h4> The optic nerve head (ONH) is a central feature of the retina, affected in many human ocular pathologies, yet it has remained underexplored in most mouse models of disease. We hypothesize that the analysis of the ONH can yield valuable insight into the phenotype of retinal diseases and that pathological changes can be detected using state-of-the-art optical coherence tomography (OCT). <h4>Methods...

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Literature Corpus work
39223b78-916b-53d4-987e-6570c57120a9
DOI
10.64898/2026.04.10.717687
Open publication

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