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Article

Comparative Investigation of the Retinal Phenotype of Three Mouse Models of Alzheimer's Disease With Optical Coherence Tomography.

Investigative ophthalmology & visual science - 3 Nov 2025

Ladurner Georg, Harper Danielle J, May Lucas, Worm Sybren, Patel Yash, Varaka Maria, Prokesch Manuela, Garhöfer Gerhard, Merkle Conrad, Baumann Bernhard

Abstract excerpt

Purpose: Mouse models of Alzheimer's disease (AD) are designed to replicate a multitude of pathologies. However, a direct comparison between models is virtually impossible due to vastly differing data acquisition and image processing protocols. Based on the hypothesis that a well-defined experimental framework is key to determining subtle differences in their retinal phenotype, we use a standardized anesthesia...

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Identifiers

PMID: 41235867
DOI: 10.1167/iovs.66.14.35
PMCID: PMC12636989

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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