Article

Early skin seeding regulatory T cells modulate PPARγ-dependent skin pigmentation

2023-10-18

Abstract excerpt

The maintenance of adult tissue homeostasis is dependent on the functional cross-talk between stem cells (SCs) and tissue-resident immune cells. This reciprocal relationship is also essential for tissue organogenesis during early life. The skin harbors a relatively large population of Regulatory T cells (Tregs) that accumulate within the first two weeks after birth. A functional role for early skin seeding Tregs (...

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Literature Corpus work: 9bd231be-8270-5274-ae68-6b75cb08040e
DOI: 10.1101/2023.10.17.561843

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