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A single-cell transcriptome atlas of pig skin reveals cellular heterogeneity from embryonic development to postnatal aging

2 Sept 2025

Abstract excerpt

BACKGROUND: Mammalian skin exhibits profound cellular and molecular restructuring across lifespan, yet an integrated single-cell mapping from embryogenesis to senescence remains limited. The Chenghua (CH) pig, with exceptional skin thickness characteristics, provides a promising model for investigating human skin development and physiology. RESULTS: We constructed a comprehensive single-cell RNA atlas of 443,529...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40898171
DOI: 10.1186/s12915-025-02390-w

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