Article
Comprehensive profiling of polyclonal sera targeting a non-enveloped viral capsid
2022-12-21
Abstract excerpt
Despite their fundamental role in resolving viral infections, our understanding of how polyclonal neutralizing antibody responses target non-enveloped viruses remains limited. To define these responses, we obtained the full antigenic profile of multiple human and mouse polyclonal sera targeting the capsid of a prototypical picornavirus. Our results uncover significant variation in the breadth and strength of neutr...
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Identifiers and source
- Literature Corpus work
- 9bc8378e-c8c1-5ac1-add0-5d1789703e0d
- DOI
- 10.1101/2022.12.21.521426