Article
Comprehensive profiling of neutralizing polyclonal sera targeting coxsackievirus B3.
Nature communications - 12 Oct 2023
Álvarez-Rodríguez Beatriz, Buceta Javier, Geller Ron
Abstract excerpt
Despite their fundamental role in resolving viral infections, our understanding of how polyclonal neutralizing antibody responses target non-enveloped viruses remains limited. To define these responses, we obtained the full antigenic profile of multiple human and mouse polyclonal sera targeting the capsid of a prototypical picornavirus, coxsackievirus B3. Our results uncover significant variation in the breadth...
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