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Predicting response and toxicity to immune checkpoint inhibitors in lung cancer using antibodies to frameshift neoantigens

2023-02-01

Abstract excerpt

<title>Abstract</title><p><bold>Purpose:</bold>To evaluate a new class of blood-based biomarkers, anti-frameshift peptide antibodies, for predicting both tumor responses and adverse immune events to immune checkpoint inhibitor (ICI) therapies in advanced lung cancer patients.<bold>Experimental Design:</bold>Serum samples were obtained from 74 lung cancer patients prior to palliative PD-(L)1 therapies with subseque...

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Literature Corpus work
9b98db33-b2ed-55d1-9e51-d1835dccf3d5
DOI
10.21203/rs.3.rs-2472861/v1
Open publication

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Predicting response and toxicity to immune checkpoint inhibitors in lung cancer using antibodies to frameshift neoantigensDOI 10.21203/rs.3.rs-2472861/v1
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