Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using Frameshift Peptide Arrays for Cancer Neo-Antigens Screening

20 Nov 2018

Abstract excerpt

It has been demonstrated that DNA mutations generating neo-antigens are important for an effective immune response to tumors as evident from recent clinical studies of immune checkpoint inhibitors (ICIs). Further, it was shown that frameshift peptides (FSP) generated in tumors from insertions and deletions (INDELs) of microsatellites (MS) in coding region are a very good correlate of positive response to PD1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immunotherapy and Immune Responses
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30478295
DOI: 10.1038/s41598-018-35673-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using Frameshift Peptide Arrays for Cancer Neo-Antigens ScreeningPMID 30478295Read ↗

RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for VaccinesSemantic proximity Read ↗

A library of Neo Open Reading Frame peptides (NOPs) as a sustainable resource of common neoantigens in up to 50% of cancer patientsSemantic proximity Read ↗

Comparison of Personal and Shared Frameshift Neoantigen Vaccines in a Mouse Mammary Cancer Model.Semantic proximity Read ↗

Sources of Cancer Neoantigens beyond Single-Nucleotide Variants.Semantic proximity Read ↗

Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model.Semantic proximity Read ↗

Neoantigens and genome instability: impact on immunogenomic phenotypes and immunotherapy response.Semantic proximity Read ↗

Discovery of putative breast cancer antigens using an integrative platform of genomics-driven immunoproteomics.Semantic proximity Read ↗

The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolutionSemantic proximity Read ↗

Vaccines for immunoprevention of DNA mismatch repair deficient cancersSemantic proximity Read ↗

Increased expression of peptides from non-coding genes in cancer proteomics datasets suggests potential tumor neoantigensSemantic proximity Read ↗

Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinomaSemantic proximity Read ↗

An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.