Back to search

Article

The protease interpain A of <i>Prevotella intermedia</i> promotes human oral squamous cell carcinoma cells proliferation and migration

2024-10-23

Abstract excerpt

Prevotella intermedia has been increasingly recognized as a potential contributor to oral squamous cell carcinoma (OSCC), yet the underlying mechanisms remain poorly defined. In this study, we identified interpain A (InpA), a cysteine protease secreted by P. intermedia , as a key virulence factor that promotes oral epithelial cell proliferation and OSCC cell migration. Conditioned medium (CM) derived from P. int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9b94f21a-e2e5-5a92-a329-372dfaf04481
DOI
10.1101/2024.10.20.619282
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The protease interpain A of <i>Prevotella intermedia</i> promotes human oral squamous cell carcinoma cells proliferation and migrationDOI 10.1101/2024.10.20.619282
Current research progress on Prevotella intermedia and associated diseasesSemantic proximity
Innocent until proven guilty: <i>Tannerella forsythia</i> may attenuate the virulence of <i>Porphyromonas gingivalis</i>Semantic proximity
<i>In vitro</i> analysis of <i>Fusobacterium Polymorphum</i> from oral leukoplakia patients identifies “high-risk” isolatesSemantic proximity
Proteome variation among <scp><i>F</i></scp><i>ilifactor alocis</i> strainsSemantic proximity
Metallo-protease Peptidase M84 from <i>Bacillus altitudinis</i> induces ROS dependent apoptosis in ovarian cancer cells by targeting PAR-1Semantic proximity
Identification of commensals and molecular components mediating trypsin degradation in the large intestineSemantic proximity
Microbial Peptidyl-Prolyl <i>cis</i> / <i>trans</i> Isomerases (PPIases): Virulence Factors and Potential Alternative Drug TargetsSemantic proximity
The effect of environmental conditions on expression of Bacteroides fragilis and Bacteroides thetaiotaomicron C10 protease genesSemantic proximity
A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain ASemantic proximity
Activation of SARS-CoV-2 by trypsin-like proteases in the clinical specimens of patients with COVID-19Semantic proximity
Antagonistic mechanisms of probiotic <i>Aliivibrio</i> sp. strain Vl2 against <i>Moritella viscosa</i> : Evidence from co-cultivation and transcriptomic analysisSemantic proximity
Immune-related function and pro-phenol oxidase system regulation of pacifastin-type serine protease inhibitor in Eriocheir sinensisSemantic proximity
Select a neighboring publication to make it the new centre.