Article

Innocent until proven guilty: <i>Tannerella forsythia</i> may attenuate the virulence of <i>Porphyromonas gingivalis</i>

2025-09-05

Abstract excerpt

<h4>ABSTRACT</h4> Periodontitis is caused by a dysbiotic microbiome beneath the gum line, primarily driven by the major pathobionts Porphyromonas gingivalis ( Pg ) and Tannerella forsythia ( Tf ). Their virulence depends on the excessive, uncontrolled activity of secreted proteases that sustain chronic inflammation, leading to the destruction of tissues supporting the tooth. Paradoxically, Tf also encodes mu...

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Literature Corpus work: 3aa3677a-9f95-58ac-a5a5-80e22c48d5b5
DOI: 10.1101/2025.09.05.674453

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