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Immune-related function and pro-phenol oxidase system regulation of pacifastin-type serine protease inhibitor in Eriocheir sinensis

28 Apr 2025

Abstract excerpt

Pacifastin is a multifunctional family of serine protease inhibitors that is conserved among the arthropods and regulates diverse physiological processes, such as activating the pro-phenol oxidase (proPO) system. However, the specific immunological roles of pacifastin in Eriocheir sinensis remain elusive. In this study, pacifastin was heterologously expressed in Escherichia coli and exhibited considerable...

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PMID: 40306379
DOI: 10.1016/j.fsi.2025.110364

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