Article

Transcriptional evaluation of the ductus arteriosus at the single-cell level uncovers a requirement for vimentin for complete closure

2021-11-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>OBJECTIVE</h4> Failure to close the ductus arteriosus immediately post-birth, patent ductus arteriosus (PDA), accounts for up to 10% of all congenital heart defects. Despite significant advances in PDA management options, including pharmacological treatment targeting the prostaglandin pathway, a proportion of patients fail to respond and must undergo surgical intervention. Thus, further ref...

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Literature Corpus work: 9b7990cb-7867-5fe4-9c93-d2793f6f4efb
DOI: 10.1101/2021.10.30.466605

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