Article

The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture

2019-02-27

Abstract excerpt

The tumour microenvironment (TME) forms a major obstacle in effective cancer treatment and for clinical success of immunotherapy. Conventional co-cultures have shed light into multiple aspects of cancer immunobiology, but they are limited by the lack of physiological complexity. We developed a novel human, organotypic skin melanoma culture (OMC) that allows real-time study of host-malignant cell interactions withi...

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Literature Corpus work: 0a9baea1-8d9e-5893-8dfa-cae7cff8f7e1
DOI: 10.1101/561530

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