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Article

The potential role of Hippo pathway regulates cellular metabolism via signaling crosstalk in disease-induced macrophage polarization.

Frontiers in immunology - 1 Jan 2023

An Yina, Tan Shuyu, Yang Jingjing, Gao Ting, Dong Yanjun

Abstract excerpt

Macrophages polarized into distinct phenotypes play vital roles in inflammatory diseases by clearing pathogens, promoting tissue repair, and maintaining homeostasis. Metabolism serves as a fundamental driver in regulating macrophage polarization, and understanding the interplay between macrophage metabolism and polarization is crucial for unraveling the mechanisms underlying inflammatory diseases. The intricate...

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PMID: 38274792
DOI: 10.3389/fimmu.2023.1344697
PMCID: PMC10808647

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