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CRISPR-Cas9 and PiggyBac Mediated Genetic Modification of Sand Fly Vectors Targeting Olfactory and Non-Lethal Phenotypic Genes

2026-02-25

Abstract excerpt

Leishmania spp. are protozoan parasites transmitted by female sand flies (Diptera) that cause a spectrum of devastating human pathologies affecting millions. Control of leishmaniases has proved immensely difficult: vector control strategies remain challenging and available chemotherapeutics imperfect. Gene editing of insect vectors offers prospects to interrupt disease transmission; for example by introducing anti...

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Literature Corpus work
9b6198b7-6b10-5442-9a83-995a8de31f89
DOI
10.64898/2026.02.24.707685
Open publication

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