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CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males

19 Feb 2024

Abstract excerpt

Rapid spread of insecticide resistance among anopheline mosquitoes threatens malaria elimination efforts, necessitating development of alternative vector control technologies. Sterile insect technique (SIT) has been successfully implemented in multiple insect pests to suppress field populations by the release of large numbers of sterile males, yet it has proven difficult to adapt to Anopheles vectors. Here we...

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PMID: 38374393
DOI: 10.1038/s41598-024-54498-8

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