Development of a toolkit for piggyBac-mediated integrative transfection of the human filarial parasite Brugia malayi

Abstract excerpt

BACKGROUND: The human filarial parasites cause diseases that are among the most important causes of morbidity in the developing world. The elimination programs targeting these infections rely on a limited number of drugs, making the identification of new chemotherapeutic agents a high priority. The study of these parasites has lagged due to the lack of reverse genetic methods. METHODOLOGY/PRINCIPAL FINDINGS: We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Insect symbiosis and bacterial influences
• Share to Lysosomal Storage Disorders Research
• Share to Parasitic Diseases Research and Treatment