Article

Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors

2022-02-10

Abstract excerpt

Severe coronavirus disease 2019 (COVID-19) is characterized by systemic inflammation and can result in protracted symptoms. Robust systemic inflammation may trigger persistent changes in hematopoietic cells and innate immune memory through epigenetic mechanisms. We reveal that rare circulating hematopoietic stem and progenitor cells (HSPC), enriched from human blood, match the diversity of HSPC in bone marrow, ena...

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Literature Corpus work: 9b56b70d-2204-5ec0-beb5-5fc328327964
DOI: 10.1101/2022.02.09.479588

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