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Anticancer Structure-Activity Relationship in Well-Characterized Pt(IV) Compounds: Pt(CH<sub>3</sub>)<sub>2</sub>I<sub>2</sub>{6,6’-dimethyl-2,2’-bipyridine} Cytotoxicity Against Colon and Ovarian Carcinoma Cell Lines

2026-03-18

Abstract excerpt

Well-defined, small-molecule, platinum-centered coordination compounds are of continued interest in both basic and applied research, particularly in medicinal chemistry and pharmaceuticals (i.e., cisplatin). Organoplatinum(IV) complexes have been reported to exhibit substantial in vitro cytotoxicity across a range of cancer cell lines. Compared with coordinatively unsaturated platinum(II) species, electronically a...

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Literature Corpus work
9b4a532b-41ba-5ec4-b7e7-a3e136670d99
DOI
10.20944/preprints202603.1427.v1
Open publication

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Anticancer Structure-Activity Relationship in Well-Characterized Pt(IV) Compounds: Pt(CH<sub>3</sub>)<sub>2</sub>I<sub>2</sub>{6,6’-dimethyl-2,2’-bipyridine} Cytotoxicity Against Colon and Ovarian Carcinoma Cell LinesDOI 10.20944/preprints202603.1427.v1
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