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ROS-mediated antitumor activity, apoptosis, and molecular docking studies of platinum (II) coordination complexes bearing 2-(diphenylphosphino)pyridine ligand

2022-10-17

Abstract excerpt

<title>Abstract</title> <p>In this study, the cytotoxicity of platinum (II) complexes containing 2-(diphenylphosphino)pyridine (dppy) ligands with a general formula of [<italic>cis</italic>- PtX<sub>2</sub>(κ<sup>1</sup> <italic>P</italic>-dppy)<sub>2</sub>], (X = Cl (<bold>1a</bold>), <italic>p</italic>-tolyl (<bold>1b</bold>) and Me (<bold>1c)</bold>) on human lung (A549), ovarian (SKOV3), breast (MCF-7) cancer...

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Literature Corpus work
34bec14e-4f61-5770-8089-74b6981a3e25
DOI
10.21203/rs.3.rs-2155062/v1
Open publication

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ROS-mediated antitumor activity, apoptosis, and molecular docking studies of platinum (II) coordination complexes bearing 2-(diphenylphosphino)pyridine ligandDOI 10.21203/rs.3.rs-2155062/v1
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