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Biological Activity of Two Anticancer Pt Complexes with a Cyclohexylglycine Ligand against a Colon Cancer Cell Line: Theoretical and Experimental Study

5 Oct 2022

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Because of their extraordinary ability to disrupt the natural structure of nucleic acids, metal complexes could be used in cancer therapy. In this study, cyclohexylglycine ( HL ) as a ligand and two new Pt complexes, [Pt(NH 3 ) 2 (L)]NO 3 ( 1 ) and [Pt(bipy)(L)]NO 3 ( 2 ), were synthesized and characterized by elemental analysis, LC-MS, UV–vis spectrometry,...

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PMID: 36385884
DOI: 10.1021/acsomega.2c03776

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