Cytotoxic Salan–Titanium(IV) Complexes: High Activity Toward a Range of Sensitive and Drug‐Resistant Cell Lines, and Mechanistic Insights

Abstract excerpt

The cytotoxicities of highly efficient salan-Ti(IV) complexes toward a range of cell lines, including drug-resistant cells, are reported along with preliminary mechanistic insights. Five salan-Ti(IV) complexes were investigated toward eight different human and murine cancer-derived cell lines, including colon, ovarian, lung, cervical, pancreatic, leukemic, skin, and breast. The salan complexes are more active...

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