Article

Pan-Omics Fusion and Machine Learning Unveil Congenital Tooth Agenesis-Ecto-mesodermal Diseases Link and Biomarker Discovery

2025-03-11

Abstract excerpt

<h4>Background</h4> Congenital tooth agenesis (CTA) is a common developmental anomaly with complex genetic and molecular mechanisms. Previous studies have primarily focused on candidate gene mutations, often lacking a pan-omics perspective. <h4>Methods</h4> This study integrates metabolomics, proteomics, microarray, and genomics with machine learning to identify biomarkers and elucidate disease mechanisms. A ran...

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Literature Corpus work: c7bf2dff-7b54-5722-bacd-8969cd7570cf
DOI: 10.1101/2025.03.09.25323497

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