Article

Transcriptional states of lung cancer microenvironment reveal macrophage subtype dynamics linked to disease progression

2025-05-23

Abstract excerpt

<title>Abstract</title> <p>The tumor microenvironment (TME) plays a pivotal role in shaping immune responses and therapeutic outcomes in lung cancer, yet the diversity and functional specialization of tumor-associated macrophages (TAMs) remain poorly resolved. Here, we present a refined classification of TAM subtypes across large cohorts of cancer datasets using integrative analysis of single-cell RNA sequencing,...

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Literature Corpus work: 9b10051d-5354-5fd5-810b-b094e4cb0d6f
DOI: 10.21203/rs.3.rs-6719524/v1

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