Article

Whisker stimulation alleviate ASD behavior of BTBR mice by regulating Piezo2 expression in DRG and neuron function in S1 and mPFC

2023-03-22

Abstract excerpt

<h4>Background: </h4> Individuals with autism spectrum disorder (ASD) commonly experience sensory abnormalities, including tactile sensation, in addition to social and repetitive restrictive behavior. This study aimed to evaluate the tactile response characteristics of children with ASD and its correlation with core phenotypes, as well as investigate the role of Piezo2 mechanically sensitive ion channels in the ta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9abc9a00-ec35-5e50-a2b1-483559020078
DOI: 10.21203/rs.3.rs-2699464/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whisker stimulation alleviate ASD behavior of BTBR mice by regulating Piezo2 expression in DRG and neuron function in S1 and mPFCDOI 10.21203/rs.3.rs-2699464/v1Read

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.Semantic proximity Read

Mechanisms of Tactile Sensory Phenotypes in Autism: Current Understanding and Future Directions for Research.Semantic proximity Read

Gene expression profiling in trigeminal ganglia from Cntnap2 -/- and Shank3b -/- mouse models of autism spectrum disorderSemantic proximity Read

Somatosensory processing deficits and altered cortico-hippocampal connectivity in Shank3b −/− miceSemantic proximity Read

Primary sensory neuron dysfunction underlying mechanical itch hypersensitivity in a Shank3 mouse model of autismSemantic proximity Read

Mouse behavioral genomics identifies Creld1 as a gatekeeper of somatosensationSemantic proximity Read

Behavioral and Sensory Deficits Associated with Dysfunction of GABAergic System in a Novel shank2-Deficient Zebrafish Model.Semantic proximity Read

Comparable tactile sensitivity between males and females on the autism spectrumSemantic proximity Read

Brief Report: Sensory processing phenotypes in Phelan-McDermid Syndrome and SYNGAP1-related Intellectual DisabilitySemantic proximity Read

Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A -associated ASDSemantic proximity Read

Sex differences in autism spectrum disorder: behavioral and sensory phenotypes in humans and mouse models.Semantic proximity Read

The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in miceSemantic proximity Read