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Article

Mechanisms of Tactile Sensory Phenotypes in Autism: Current Understanding and Future Directions for Research.

Current psychiatry reports - 5 Dec 2019

Schaffler Melanie D, Middleton Leah J, Abdus-Saboor Ishmail

Abstract excerpt

PURPOSE OF REVIEW: This review aims to summarize the current body of behavioral, physiological, and molecular knowledge concerning tactile sensitivity in autism spectrum disorder (ASD), with a focus on recent studies utilizing rodent models. RECENT FINDINGS: Mice with mutations in the ASD-related genes, Shank3, Fmr1, UBE3A, and Mecp2, display tactile abnormalities. Some of these abnormalities appear to be caused...

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PMID: 31807945
DOI: 10.1007/s11920-019-1122-0
PMCID: PMC6900204

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