Article

Comparative Modelling of Actin–Tropomyosin Interfaces

2026-07-10

Abstract excerpt

Tropomyosins are coiled-coil dimers that polymerize head-to-tail along actin filaments. They stabilize distinct filament populations and regulate the access of myosins and actin-binding proteins in both muscle and non-muscle contexts. Despite their central regulatory role, how filament length and isoform identity of different tropomyosin homologues might modulate actin affinity is not completely understood, especi...

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Literature Corpus work: 9a9e0f0b-46f7-5227-bbe3-4cad8148757d
DOI: 10.64898/2026.07.06.736648

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