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Article

A peek into tropomyosin binding and unfolding on the actin filament.

PloS one - 24 Jul 2009

Singh Abhishek, Hitchcock-Degregori Sarah E

Abstract excerpt

BACKGROUND: Tropomyosin is a prototypical coiled coil along its length with subtle variations in structure that allow interactions with actin and other proteins. Actin binding globally stabilizes tropomyosin. Tropomyosin-actin interaction occurs periodically along the length of tropomyosin. However, it is not well understood how tropomyosin binds actin. PRINCIPAL FINDINGS: Tropomyosin's periodic binding sites...

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Identifiers

PMID: 19629180
DOI: 10.1371/journal.pone.0006336
PMCID: PMC2710508

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Source receipt: pubmed, retrieved 7 Sept 2026.

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