Article

CCFold: rapid and accurate prediction of coiled-coil structures and application to modelling intermediate filaments

2017-04-14

Abstract excerpt

Accurate molecular structure of the protein dimer representing the elementary building block of intermediate filaments (IFs) is essential towards the understanding of the filament assembly, rationalizing their mechanical properties and explaining the effect of disease-related IF mutations. The dimer contains a ∼300-residue long α -helical coiled coil which is not assessable to either direct experimental structure...

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Literature Corpus work: 1a58ceb4-1920-5dff-9a8a-d76ba95805df
DOI: 10.1101/123869

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