Article

Reduced response to SARS-CoV-2 vaccination is associated with impaired immunoglobulin class switch recombination in SLE patients

2024-08-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Systemic Lupus Erythematosus (SLE) patients exhibit B-cell abnormalities. Although there are concerns about reduced antibody responses to SARS-CoV-2 vaccines, detailed data on B-cell-specific responses in SLE remain scarce. Understanding the responsiveness to novel vaccine-antigens, and boosters number, is important to avoid unnecessary prolonged isolation of immunocompromised...

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Literature Corpus work: 9a2293bf-93a6-5bea-bce9-5f922ea537fa
DOI: 10.1101/2024.08.14.24310924

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