Article

MeXpose - A modular imaging pipeline for the quantitative assessment of cellular metal bioaccumulation

2023-12-15

Abstract excerpt

We introduce MeXpose, an imaging pipeline for single-cell metallomics by laser ablation inductively coupled plasma time-of-flight mass spectrometry (LA-ICP-TOFMS). MeXpose is designed for mechanistic studies on metal exposure unravelling cellular phenotypes and tissue level characteristics of metal bioaccumulation. MeXpose leverages the high-resolution capabilities of low-dispersion laser ablation setups, a standa...

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Literature Corpus work: 99b916f2-0256-5fbd-9767-12350d3b1c72
DOI: 10.1101/2023.12.15.571675

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