Article

Integration of Elemental Imaging and Spatial Transcriptomic Profiling for Proof-of-Concept Metals-Based Pathway Analysis of Colon Tumor Microenvironment

2024-12-10

Abstract excerpt

The complex interplay between metal abundance, transport mechanisms, cell distribution, and tumor progression-related biological pathways (e.g., metabolism, collagen remodeling) remains poorly understood. Traditionally, genes and metals have been studied in isolation, limiting insights into their interactions. Recent advances in spatial transcriptomics and elemental profiling now enable comprehensive exploration o...

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Literature Corpus work: 7eb9e896-718e-5ca6-95fa-5f72754b76c2
DOI: 10.1101/2024.12.09.24318747

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