Article

Day-night and seasonal variation of human gene expression across tissues

2021-03-01

Abstract excerpt

Circadian and circannual cycles trigger physiological changes whose reflection on human transcriptomes remains largely uncharted. We used the time and season of death of 932 individuals from GTEx to jointly investigate transcriptomic changes associated with those cycles across multiple tissues. Overall, most variation across tissues during day-night and among seasons was unique to each cycle. Although all tissues...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 99b76c7a-0384-5e63-b932-6a9b1364bdaf
DOI: 10.1101/2021.02.28.433266

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Day-night and seasonal variation of human gene expression across tissuesDOI 10.1101/2021.02.28.433266Read

Day-night and seasonal variation of human gene expression across tissuesSemantic proximity Read

Non-human primate seasonal transcriptome atlas reveals seasonal changes in physiology and diseasesSemantic proximity Read

Local clocks within human tissues reveal widespread 24-hour rhythms in gene expressionSemantic proximity Read

Differential Phasing between Circadian Clocks in the Brain and Peripheral Organs in HumansSemantic proximity Read

Sex-dimorphic and age-dependent organization of 24 hour gene expression rhythms in humanSemantic proximity Read

Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humansSemantic proximity Read

A population-based human enCYCLOPedia for circadian medicineSemantic proximity Read

Gene networks under circadian control exhibit diurnal organization in primate organsSemantic proximity Read

Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human AgingSemantic proximity Read

Widespread seasonal gene expression reveals annual differences in human immunity and physiologySemantic proximity Read

Seasonal Effects on Gene ExpressionSemantic proximity Read

Large-scale analysis of temporal gene expression variation in peripheral blood.Semantic proximity Read