Article

Msp1/ATAD1 restores mitochondrial function in Zellweger Spectrum Disease

2020-09-19

Abstract excerpt

Peroxisomal Biogenesis Disorders (PBDs) are a class of inherited metabolic disorders with profound neurological and other phenotypes. The most severe PBDs are caused by mutations in peroxin genes, which result in nonfunctional peroxisomes typically through impaired protein import. In order to better understand the molecular causes of Zellweger Spectrum Disease (ZSD) -the most severe PBDs -, we investigated the fat...

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Literature Corpus work: 99a73dc5-e469-59b1-b789-066a47b7c9fd
DOI: 10.1101/2020.09.19.303826

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