Article
Proteasome-dependent protein quality control of the peroxisomal membrane protein Pxa1p.
Biochimica et biophysica acta. Biomembranes - 1 Sept 2020
Devarajan S, Meurer M, van Roermund C W T, Chen X, Hettema E H, Kemp S, Knop M, Williams C
Abstract excerpt
Peroxisomes are eukaryotic organelles that function in numerous metabolic pathways and defects in peroxisome function can cause serious developmental brain disorders such as adrenoleukodystrophy (ALD). Peroxisomal membrane proteins (PMPs) play a crucial role in regulating peroxisome function. Therefore, PMP homeostasis is vital for peroxisome function. Recently, we established that certain PMPs are degraded by...
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