Article

Syntaxin-3 regulates Tight Junction Assembly in Human Retinal Pigment Epithelium

2026-02-02

Abstract excerpt

The retinal pigment epithelium (RPE) consists of polarized epithelial cells, serving as a support system for photoreceptor maintenance, where the polarity is contributed by the distribution of syntaxins (STX) within the cell. STX3, a known regulator of apical trafficking in epithelial cells, was previously understood to be absent in human RPE cells, with its functions thought to be compensated by STX1A. However, o...

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Literature Corpus work: 9952c027-8379-5342-8126-cc98e6e3a5c0
DOI: 10.64898/2026.01.30.702706

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