Article
The use of canine models of inherited retinal degeneration to test novel therapeutic approaches.
Veterinary ophthalmology - 1 Jan 2000
Beltran William A
Abstract excerpt
Inherited retinal degenerations (RDs) are a common cause of blindness in dogs and in humans. Over the past two decades numerous genes causally associated with these diseases have been identified and several canine models have been used to improve our understanding of the molecular mechanisms of RDs, as well as to test the proof of principle and safety of novel therapies. This review briefly summarizes the drug...
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