Article

Tissue- and sex-specific DNA damage tracks aging in rodents and humans

2022-11-29

Abstract excerpt

<h4>Summary</h4> DNA damage causes genomic instability underlying many human diseases. Traditional approaches to DNA damage analysis provide minimal insights into the spectrum of disease-driving DNA lesions and the mechanisms causing imbalances in damage formation and repair. Here we used untargeted mass spectrometry-based adductomics 1 to discover 114 putative DNA lesions and modifications consistently detected...

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Identifiers and source

Literature Corpus work: 98f035e0-63d4-595a-90e9-57429505d70d
DOI: 10.1101/2022.11.28.518087

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