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IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells

2022-04-14

Abstract excerpt

<h4>Background</h4> Antigenic stimulation through cross-linking the IgE receptor and epithelial cell-derived cytokine IL-33 are potent stimuli of mast cell (MC) activation. Moreover, IL-33 primes a variety of cell types, including MCs to respond more vigorously to external stimuli. However, target genes induced by the combined IL-33 priming and antigenic stimulation have not been investigated in human skin mast c...

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Literature Corpus work
98f006a2-399c-51fb-826c-4ccf65f3a746
DOI
10.1101/2022.04.14.488379
Open publication

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