Article

γ1-adaptin expression is associated with cancer progression and poor prognosis in pancreatic ductal adenocarcinoma: Cellular and histopathological analyses

2026-05-15

Abstract excerpt

<title>Abstract</title> <p> Background The adaptor protein complex-1 (AP-1) is a clathrin adaptor involved in intracellular trafficking at the trans-Golgi network and endosomes. Despite its fundamental role in membrane trafficking, the clinical and pathological significance of the γ1-adaptin-containing AP-1 in pancreatic ductal adenocarcinoma (PDAC) remains unclear. Methods γ1-adaptin knockout PANC-1 cell line...

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Literature Corpus work: 98c16954-0d98-54f9-acbf-16bcc293a90e
DOI: 10.21203/rs.3.rs-9301878/v1

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