Article

Field cancerization impacts tumor development, T-cell exhaustion and clinical outcomes in bladder cancer

2023-02-21

Abstract excerpt

Bladder field cancerization may be associated with disease outcome in patients with bladder cancer. To investigate this, we analyzed biopsies from bladder urothelium and urine samples by genomics and proteomics analyses. Samples were procured from multiple timepoints from 134 patients with early stage bladder cancer and detailed long term follow-up. We measured the field cancerization in normal-appearing bladder b...

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Literature Corpus work: 98acba40-198b-5d5c-b498-20211dd54f3c
DOI: 10.1101/2023.02.20.528920

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