Article

Comparing Expression of OAS-RNaseL Pathway-Related Genes in SARS-CoV-2 and Similar Viruses

2021-04-30

Abstract excerpt

The COVID-19 pandemic, caused by the virus SARS-CoV-2, has been a major public health emergency and has caused millions of deaths worldwide to date. Due to the novel nature of the virus, efforts across the world are underway to better understand the molecular pathogenesis of SARS-CoV-2 and how it interacts with host immune responses. One important branch of the innate immune response, the interferon system, trigge...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 989106cd-0faf-534b-ade2-605fb7ef1e5e
DOI: 10.1101/2021.04.29.442063

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparing Expression of OAS-RNaseL Pathway-Related Genes in SARS-CoV-2 and Similar VirusesDOI 10.1101/2021.04.29.442063Read

Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver PathologySemantic proximity Read

Comprehensive comparison of transcriptomes in SARS-CoV-2 infection: alternative entry routes and innate immune responsesSemantic proximity Read

Mechanisms of impairment of interferon production by SARS-CoV-2Semantic proximity Read

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1Semantic proximity Read

<i>In vivo</i> antiviral host response to SARS-CoV-2 by viral load, sex, and ageSemantic proximity Read

SARS-CoV-2-Encoded MiRNAs Inhibit Host Type I Interferon Pathway and Mediate Allelic Differential Expression of Susceptible Gene.Semantic proximity Read

Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases.Semantic proximity Read

Host transcriptional response to SARS-CoV-2 infection in COVID-19 patientsSemantic proximity Read

Perversely expressed long noncoding RNAs can alter host response and viral proliferation in SARS-CoV-2 infectionSemantic proximity Read

Gene expression profiling of SARS-CoV-2 infections reveal distinct primary lung cell and systemic immune infection responses that identify pathways relevant in COVID-19 diseaseSemantic proximity Read

Comparative transcriptome analysis reveals the intensive early-stage responses of host cells to SARS-CoV-2 infectionSemantic proximity Read

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial CellsSemantic proximity Read