Article

Comparative transcriptome analysis reveals the intensive early-stage responses of host cells to SARS-CoV-2 infection

2020-05-01

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a widespread outbreak of highly pathogenic COVID-19. It is therefore important and timely to characterize interactions between the virus and host cell at the molecular level to understand its disease pathogenesis. To gain insights, we performed high-throughput sequencing that generated time-series data simultaneously for bioinformatics analysi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 23efbe8a-7fbe-578f-a3d3-d75a0d9c34f4
DOI: 10.1101/2020.04.30.071274

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative transcriptome analysis reveals the intensive early-stage responses of host cells to SARS-CoV-2 infectionDOI 10.1101/2020.04.30.071274Read

Comparative Transcriptome Analysis Reveals the Intensive Early Stage Responses of Host Cells to SARS-CoV-2 InfectionSemantic proximity Read

Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral loadSemantic proximity Read

Host transcriptome alterations in vitro and in vivo following severe acute respiratory syndrome coronavirus 2 infectionSemantic proximity Read

Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral loadSemantic proximity Read

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1Semantic proximity Read

Viral and Host Transcriptomes in SARS-CoV-2-Infected Human Lung CellsSemantic proximity Read

Gene expression profiling of SARS-CoV-2 infections reveal distinct primary lung cell and systemic immune infection responses that identify pathways relevant in COVID-19 diseaseSemantic proximity Read

Bioinformatics analysis of single-cell mRNA-seq of SARS-CoV-1 and SARS-CoV-2 infection compared to MERS-CoV from Sequence Read Archive (SRA) database reveals novel targets for therapiesSemantic proximity Read

Comprehensive comparison of transcriptomes in SARS-CoV-2 infection: alternative entry routes and innate immune responsesSemantic proximity Read

Decoding Viral Signatures: Comparative Transcriptomics of SARS-CoV-2, Influenza A, and RSV Reveals Virus-Specific Host ResponsesSemantic proximity Read

SARS-CoV-2 and the host-immune responseSemantic proximity Read

The molecular biology of SARS-CoV-2 pathogenesis, host genetics and associated interactions in infectionSemantic proximity Read