Article

BiFCo: Visualising cohesin assembly/disassembly cycle in living cells

2023-01-22

Abstract excerpt

Cohesin is a ring-shaped protein complex highly conserved in evolution that is composed in all eukaryotes of at least two SMC proteins (Structural Maintenance of Chromosomes) SMC1 and SMC3 in humans (Psm1 and Psm3 in fission yeast), and the kleisin RAD21 (Rad21 in fission yeast). Mutations in its components or its regulators cause genetic syndromes (known as cohesinopathies) and several types of cancer. It has bee...

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Literature Corpus work: 9866856c-e8fb-52b3-a2e2-83be0e812808
DOI: 10.1101/2023.01.21.525018

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