Article

Accumulation of SA-βGal–High Cells in Human Naïve T Cell Compartments Reveals a Stress-Adapted, Senescent-Like State

2025-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Aging is associated with a decline in immune function termed immunosenescence, characterized by accumulation of senescent-like immune cells and chronic inflammation, known as inflammaging. While senescence-associated β-galactosidase (SA-βGal) activity is a well-established senescence marker, its functional significance and the precise cellular subsets affected within the T cell compartment remai...

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Literature Corpus work: 98458053-bc75-5b83-875c-1bf7c2fd4e77
DOI: 10.1101/2025.06.10.658841

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